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(詳細はlocal anesthetic agents can be toxic if used in excessive doses or administered improperly. Even when administered properly, patients may still experience unintended reactions to local anesthetics.〔Zamanian, R., Toxicity, Local Anesthetics (2005)〕 Excessive doses may be unintentionally administered in several ways. # Small doses of local anesthetic to achieve an adequate level of anesthesia may lead to eventual administration of toxic doses. Harm from anesthesia is not very common and only occurs with large doses. # Injection of anesthesia in a confined space may result in excessive fluid pressure that may damage nerves. # Doses intended for epidural or intra-support-tissue administration may be accidentally delivered as intravascular injection, resulting in accelerated systematic absorption.〔 The toxic effects of local anesthetics can be classified by localized and systemic effects. ==Toxicity== 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Local anesthetic toxicity」の詳細全文を読む スポンサード リンク
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